Tim Kosfeld

Because infection causes expansion of pathogen specific T cells that express pathogen specific unique receptors encoded in DNA, exposure history of an individual can be accessed through examination of their T-cell receptors (TCRs). These unique sequences can be used as biomarkers for tracking T-cell responses and cataloging immunological history. The... [Read More]

Structural variants (SV) are recognized as a prominent source of genetic variation, with single variants manifesting significant influence over phenotypic expression. However, their effects remain poorly understood due to computational limitations and a continued focus on SNPs. Addressing this need, we introduce the Variant Identification Pipeline with Expression Realization (VIPER),... [Read More]